At the age of seven, Mothersbaugh began wearing glasses to correct his severe myopia and astigmatism, before which he was legally blind. Over the years, he took an interest in designing his own distinctive eyewear for use in Devo shows.

The theme song for Rugrats is composed by Mark Mothersbaugh, who also composed the main music for the series, along with Denis M. Hannigan, Rusty Andrews, and his brother Bob Mothersbaugh.

Rugrats Theme Song is a theme song written by Mark Mothersbaugh that plays before the beginning of every Rugrats episode. The original version appeared in the original series, while it was remixed twice in both the later episodes of the original series and the revival.